The Center for Advanced Imaging is a research and innovation center created by Harvard to pool expertise in physics, chemistry, biology, engineering, and computer science to invent the next generation of imaging technologies that will enable direct visualization of the molecular and cellular interactions inside living systems. Through these unprecedented imaging capabilities, the Center will establish new pathways towards understanding how living systems function, and how things go wrong in disease.
Inside the human body reside numerous different types of cells, which are in turn composed of hundreds of thousands of different molecular species, including DNA, RNA, proteins, and small molecules. Both the molecules and the cells interact through intricate networks to give rise to the emergent phenomenon of life. Understanding these molecular and cellular interaction networks, how they work in normal states, and how they go wrong in diseased states, is essential for unraveling the mystery of life and the...
Harvard John A. Paulson School of Engineering and Applied Sciences
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The research programs within the Center work to advance and invent technologies that expand the current tool set for observing living systems at the molecular and celluilar scale. These technologies are then applied to projects focused on addressing critically important scientific questions in biology and medicine.
The Center for Advanced Imaging at Harvard is located in the Northwest Building (52 Oxford Street, Cambridge, MA 02138), a multi-disciplinary research building designed to enhance collaboration and housing neuroscience, bioengineering, computational analysis and other programs under one roof. It has become a model for a new generation of research environments.
The Center occupies approximately 5200 square feet on two floors including a state of the art imaging laboratory (3654 square feet on the B4 floor) and office suite (1511 square feet on the ground floor). Space...
Group Leader Center for Advanced Imaging at Harvard
Dr. Babcock's research focuses on technique and algorithm development for super-resolution fluorescence microscopy using the single molecule localization approach (SMLM). Learn more >>
Northwest Building, 147
52 Oxford Street
Cambridge, MA 02138
Professor of Chemistry and Chemical Biology and of Physics Faculty of Arts and Sciences Chemistry and Chemical Biology
Professor Cohen's research focuses on developing and applying new physical tools to study molecules, cells, and organisms. His research group invents new tools to probe biological structures and uses them to make new measurements. They combine protein engineering, lasers, nanofabrication, microfluidics, electronics, biochemistry, and computers to generate data; and apply statistics and physical modeling to understand the data. Current projects include: development of fluorescent voltage-indicating proteins for all-optical electrophysiology; disease modeling in human induced pluripotent stem cells; studies on the nanomechanical properties of DNA; and development of techniques that combine image processing and optogenetics for functional screens in mammalian cells. Learn more >>
Mallinckrodt Building, 115
12 Oxford Street
Cambridge, MA 02138